On 21st June 2017 the study protocol was published online by Antje Neubert, Manuel Alberto Baarslag, Monique van Dijk, Joost van Rosmalen, Joseph F Standing, Yucheng Sheng, Wolfgang Rascher, Deborah Roberts, Jackie Winslade, Louise Rawcliffe, Sara M Hanning, Tuuli Metsvaht,… read more →
On June 14th2017, the Site Initiation Visit (SIV) was held at the new building of Karolinska Institutet children’s hospital (KI) in Stockholm. The study monitor Louise Rawcliffe from Therakind Ltd. and the Sponsor (represented by Irmgard Toni) met the KI… read more →
One of the key elements of the CloSed project is the study CLON01 (EudraCT Number: 2014-003582-24 ClinicalTrials.gov Identifier: NCT02509273). After having received full authorisation from the national Competent Authorities and local Ethics Committees in the Netherlands and Germany, two study sites are presently… read more →
On October 21st, 2016 the first Investigator Meeting of the CloSed project took place in Geneva (Switzerland). The meeting was aimed to bring all principal investigators of the CLON01 study together to discuss practical clinical aspects of the CloSed trial… read more →
On October 10th-11th, 2016, the site initiation visit (SIV) was held at Ospedale Pediatrico Bambino Gesù (OPBG) in Italy. The visit’s programme stretched over two days, during which all site documentation was reviewed and the study details were presented with… read more →
A summary information for parents was developed under the guidance of the patient organisation VSOP (Vereniging Samenwerkende Ouder – en Patiëntenorganisaties). Adapted to local language, this summary information can be offered to parents in addition to the Patient Information Sheets… read more →
An informative leaflet illustrating CloSed using more direct and generally understandable language is available in English in order to raise awareness about the project to the non-scientific public. The leaflet is available here.
A mini-review of non-parenteral clonidine preparations for paediatric sedation has recently been published in the Journal of Pharmacy and Pharmacology by Dr. Sara Hanning and colleagues on behalf of the CloSed Consortium focusing on the feasibility of alternative, less invasive… read more →