Azienda Ospedaliera di Rilievo Nazionale e di Alta Specializzazione Civico, Di Cristina, Benfratelli (ARNAS-Civico)

Azienda Ospedaliera di Rilievo Nazionale e di Alta Specializzazione Civico, Di Cristina, Benfratelli (ARNAS-Civico) is based in Palermo. It includes two hospital districts, the first dedicated to care of the child, Hospital Di Cristina, and the second, the Civico Hospital, dedicated to both adults and newborns. The latter is the reference centre for management of high-risk pregnancies and newborns at high risk of morbidity and mortality in western Sicily. The Civico Hospital has 2,000 births annually, and its NICU/Neonatology Unit is a new recruitment site for neonatal patients in the CloSed study. The Unit has inborn and outborn admissions ranging around 500 patients/year and has conducted clinical studies on neonatal analgesia and Cerebral Near-Infrared Spectroscopy (NIRS) monitoring in preterm and term newborns with ischemic hypoxic encephalopathy in hypothermic treatment.