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Clonidine for Sedation of Paediatric Patients in the Intensive Care Unit

CloSed is a 5-year project funded under the Seventh Framework Programme (FP7) with an international Consortium comprising 10 European partners and coordinated by Assoc. Prof. Antje Neubert, University Hospital of Erlangen.

The project aims to conduct a multicentre clinical trial of clonidine in children until the age of 18. Indeed, despite its widespread use in Pediatric Intensive Care Units (PICU), this drug still lacks authorisation for paediatric use. A parenteral age-appropriate formulation of clonidine for sedation in PICU will be developed and tested in order to obtain a Pediatric Use Marketing Authorisation (PUMA).

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CloSed Final Project Meeting and second PAB Meeting

This 5-year project was funded under the Seventh Framework Programme (FP7) to develop and study an age-appropriate intravenous clonidine formulation... Read More →

CloSed General Assembly #4 in Prague

On April 11-12th 2018, the 4th General Assembly of the CloSed Consortium took place in Prague, Czech Rebpublic. The meeting... Read More →

European Research in Paediatrics

EU Paediatric Regulation includes provisions for funding of research into off-patent medicines leading to PUMAs. In this context, the EU launched several calls under FP7 to develop age-appropriate formulations and/or delivery systems of off-patent drugs used in paediatrics, and the CloSed project has been selected for funding.

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CloSed is an EU-funded project

CloSed is an EU-funded project

This project has received funding from the European Union’s Seventh Framework Programme for research, technological development and demonstration under grant agreement n.602453

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